Bayer Leverkusen v Atletico Madrid
The overall record between both sides is perfectly balanced with one win each and two draws, as well as three goals a piece.
However, their only previous Champions League knockout encounter in the 2014-15 last 16 saw Atletico win on penalties.
Atletico Madrid's Antoine Griezmann will be a key man against Leverkusen
There have never been more than two goals in the four encounters between both sides.
Atlético Madrid have finished top of their group in all four of their Champions League campaigns under Diego Simeone - they've also always progressed past the last 16 under their Argentinian manager.
Bayer Leverkusen have reached the knockout stages for the fifth time in their last six Champions League campaigns.
However, they haven't progressed further than the last 16 since their appearance in the 2002 final.
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